PUBLICATIONS
Research papers
ATP-release pannexin channels are gated by lysophospholipids.
Henze E, Ehrlich JJ, Burkhardt RN, Fox BW, Michalski K, Kramer L, Lenfest M, Boesch JM, Schroeder FC, and Kawate T. (2023) bioRxiv 2023.10.23.563601. doi: 10.1101/2023.10.23.563601.
GCP16 stabilizes the DHHC9 subfamily of protein acyltransferases through a conserved C-terminal cysteine motif.
Nguyen PL, Greentree WK, Kawate T, Linder ME. (2023) Front Physiol. 14:1167094. doi: 0.3389/fphys.2023.1167094
The cryo-EM structure of a pannexin 1 reveals unique motifs for ion selection and inhibition
Michalski K, Syrjanen JL, Henze E, Kumpf J, Furukawa H, and Kawate T. (2020) eLife. doi: 10.7554/eLife.54670
CAKUT and Autonomic Dysfunction Caused by Acetylcholine Receptor Mutations.
Mann N, Kause F, Henze EK, Gharpure A, Shril S, Connaughton DM, Nakayama M, Klämbt V, Majmundar AJ, Wu CW, Kolvenbach CM, Dai R, Chen J, van der Ven AT, Ityel H, Tooley MJ, Kari JA, Bownass L, El Desoky S, De Franco E, Shalaby M, Tasic V, Bauer SB, Lee RS, Beckel JM, Yu W, Mane SM, Lifton RP, Reutter H, Ellard S, Hibbs RE, Kawate T, Hildebrandt F. (2019) Am J Hum Genet. 105(6):1286-1293. doi: 10.1016/j.ajhg.2019.10.004.
The weak voltage dependence of pannexin 1 channels can be tuned by N-terminal modifications
Michalski K, Henze E, Nguyen P, Lynch P, and Kawate T. (2018) J Gen Physiol. doi: 10.1085/jgp.201711804
The P2X7 receptor forms a dye-permeable pore independent of its intracellular domain but dependent on membrane lipid composition
Karasawa A, Michalski K, Mikhelzon P, and Kawate T. (2017) eLife, 6:e31186
Structural basis for subtype-specific inhibition of the P2X7 receptor
Karasawa A and Kawate T. (2016) eLife, 5:e22153
Carbenoxolone inhibits Pannexin1 channels through interactions in the first extracellular loop
Michalski K and Kawate T. (2016) J Gen Physiol. 147(2):165-74
Membrane protein mobility and orientation preserved in supported bilayers created directly from cell plasma membrane blebs
Richards MJ, Hsia CY, Singh RR, Haider SH, Kumpf JM, Kawate T, and Daniel S. (2016) Langmuir. 32(12):2963-74.
Reviews, Methods, and Book chapters
Methods for Studying Cholesterol-Dependent Regulation of P2X7 Receptors.
Murrell-Lagnado RD, Kawate T. (2022) Methods Mol Biol. 2022;2510:253-264. doi: 10.1007/978-1-0716-2384-8_13.
On the molecular nature of large-pore channels.
Syrjanen J, Michalski K, Kawate T, Furukawa H. (2021) J Mol Biol. 433(17):166994. doi: 10.1016/j.jmb.2021.166994.
P2X Receptor Activation
Kawate T. (2017) Adv Exp Med Biol.
Expression and Purification of a Mammalian P2X7 Receptor from Sf9 insect Cells
Karasawa A and Kawate T. (2017) Bio Protoc, Sep 05;7(17)